Specimen-specific™ Inhibitor Tolerant Master Mixes
In developing universal inhibitor tolerant qPCR and RT-qPCR mixes, a compromise is required to accommodate all of the different types of inhibitors, this reduces sensitivity of the quantitative PCR. Meridian has therefore developed sample specific inhibitor tolerant qPCR and RT-qPCR formulations, designed to be used for direct amplification from crude lysates or inhibitor-rich samples either from blood, saliva, urine or stool. The ability of these mixes to tolerate the high level of PCR inhibitors present in these different sample types allows the development of simpler, faster multiplex qPCR assays that require minimal sample processing and fast turn-around times (TAT). This makes them ideal for liquid biopsy and point of care testing (POCT), where speed, sensitivity, and reproducibility are essential.
The mixes can be used as wet mixes or dried by lyophilization or air-drying, there are several advantages to this, including room temperature shipping and storage, extended shelf-life, and increased flexibility in the sample volume.
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Products (29)
| Name | Specimen Type | Application | Catalog | Order a Sample | Sizes | Description | Wet(Liquid) | Air-Dryable | Dryable | Glycerol-Free | Lyo-Ready | Concentration | High Concentration | Detail | Safety Data Sheet | COA/Test Release | User Guide | Product Handling Guide | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lyo-Ready Genotyping Direct qPCR FFPE, 4x | FFPE, Lyo-Ready Mix | SNP Genotyping | MDX168 | Order a Sample | Available in 1,000 Unit or 10,000 Unit aliquots | Better extraction buffers and greater tolerance to crude FFPE samples. Compatible with all dual-label probe chemistries for detection of genetic variants, such as single nucleotide and copy number variants, to give highly reproducible allelic discrimination. |
Yes | No | Lyo-Ready | YesYes | Yes | 4x | Yes | View Details | COA/Test Release | User Guide | Product Handling Guide | |||
| Lyo-Ready Genotyping Direct qPCR Urine, 4x | Urine, Lyo-Ready Mix | SNP Genotyping | MDX158 | Order a Sample | Available in 1,000 Unit or 10,000 Unit aliquots | Inhibitor tolerance to 20% urine. Compatible with all dual-label probe chemistries for detection of genetic variants, such as single nucleotide and copy number variants, to give highly reproducible allelic discrimination. |
Yes | No | Lyo-Ready | YesYes | Yes | 4x | Yes | View Details | Safety Data Sheet | COA/Test Release | Product Handling Guide | |||
| Lyo-Ready Direct RNA/DNA LAMP Urine, 4x | Urine, LAMP Mixes | RT-LAMP | MDX155 | Order a Sample | Available in 5 mL (1,000 Rxns) or 50 mL (10,000 Rxns) aliquots | Inhibitor tolerance to 20% urine. Perfect for multiplexing and fast cycling conditions. Used in the detection of urinary track infections, STD, tropical diseases, cancer screening, bladder and prostate cancer. |
Yes | No | Lyo-Ready | YesYes | Yes | 4x | Yes | View Details | COA/Test Release | User Guide | Product Handling Guide | |||
| Lyo-Ready Direct DNA LAMP Urine, 4x | Urine, LAMP Mixes | LAMP | MDX154 | Order a Sample | Available in 5 mL (1,000 Rxns) or 50 mL (10,000 Rxns) aliquots | Inhibitor tolerance to 20% urine. Perfect for multiplexing and fast cycling conditions. Used in the detection of urinary track infections, STD, tropical diseases, cancer screening, bladder and prostate cancer. |
Yes | No | Lyo-Ready | YesYes | Yes | 4x | Yes | View Details | COA/Test Release | User Guide | Product Handling Guide | |||
| Air-Dryable Direct DNA qPCR Stool, 4x | Stool, Air-Dryable Mix | qPCR | MDX140 | Order a Sample | Available in 5 mL (1,000 Rxns) or 50 mL (10,000 Rxns) aliquots | Inhibitor tolerance to 20% stool, 2 mg/mL bile salt and 40% Cary Blair media. Perfect for multiplexing and fast cycling conditions. Used in the detection of IBD, cancer, fecal microbiota and bacterial and viruses. |
Yes | Yes | Air-Dryable | YesYes | No | 4x | Yes | View Details | Safety Data Sheet | COA/Test Release | Product Handling Guide | |||
| Lyo-Ready Direct RNA/DNA qPCR Urine, 4x | Urine, Lyo-Ready Mix | RT-qPCR | MDX153 | Order a Sample | Available in 5 mL (1,000 Rxns) or 50 mL (10,000 Rxns) aliquots | Inhibitor tolerance to 20% urine. Perfect for multiplexing and fast cycling conditions. Used in the detection of urinary track infections, STD, tropical diseases, cancer screening, bladder and prostate cancer. |
Yes | No | Lyo-Ready | YesYes | Yes | 4x | Yes | View Details | COA/Test Release | User Guide | Product Handling Guide | |||
| Lyo-Ready Direct DNA qPCR Urine, 4x | Urine, Lyo-Ready Mix | qPCR | MDX152 | Order a Sample | Available in 5 mL (1,000 Rxns) or 50 mL (10,000 Rxns) aliquots | Inhibitor tolerance to 20% urine. Perfect for multiplexing and fast cycling conditions. Used in the detection of urinary track infections, STD, tropical diseases, cancer screening, bladder and prostate cancer. |
Yes | No | Lyo-Ready | YesYes | Yes | 4x | Yes | View Details | COA/Test Release | User Guide | Product Handling Guide | |||
| Air-Dryable Direct RNA/DNA qPCR Urine, 4x | Urine, Air-Dryable Mix | RT-qPCR | MDX151 | Order a Sample | Available in 5 mL (1,000 Rxns) or 50 mL (10,000 Rxns) aliquots | Inhibitor tolerance to 20% urine. Perfect for multiplexing and fast cycling conditions. Used in the detection of urinary track infections, STD, tropical diseases, cancer screening, bladder and prostate cancer. |
Yes | Yes | Air-Dryable | YesYes | No | 4x | Yes | View Details | Safety Data Sheet | COA/Test Release | User Guide | Product Handling Guide | ||
| Air-Dryable Direct DNA qPCR Urine, 4x | Urine, Air-Dryable Mix | qPCR | MDX150 | Order a Sample | Available in 5 mL (1,000 Rxns) or 50 mL (10,000 Rxns) aliquots | Inhibitor tolerance to 60% urine. Perfect for multiplexing and fast cycling conditions. Used in the detection of urinary track infections, STD, tropical diseases, cancer screening, bladder and prostate cancer. |
Yes | Yes | Air-Dryable | YesYes | No | 4x | Yes | View Details | Safety Data Sheet | COA/Test Release | Product Handling Guide | |||
| Lyo-Ready Genotyping Direct qPCR Stool, 4x | Stool, Lyo-Ready Mix | SNP Genotyping | MDX148 | Order a Sample | Available in 1,000 Unit or 10,000 Unit aliquots | Inhibitor tolerance to 20% stool. Compatible with all dual-label probe chemistries for detection of genetic variants, such as single nucleotide and copy number variants, to give highly reproducible allelic discrimination. |
Yes | No | Lyo-Ready | YesYes | Yes | 4x | Yes | View Details | COA/Test Release | Product Handling Guide | ||||
| Lyo-Ready Direct RNA/DNA LAMP Stool, 4x | Stool, LAMP Mixes | RT-LAMP | MDX145 | Order a Sample | Available in 5 mL (1,000 Rxns) or 50 mL (10,000 Rxns) aliquots | Inhibitor tolerance to 5% stool, 2 mg/mL bile salt and 40% Cary Blair media. Perfect for multiplexing and fast cycling conditions. Used in the detection of IBD, cancer, fecal microbiota and bacterial and viruses. |
Yes | No | Lyo-Ready | YesYes | Yes | 4x | Yes | View Details | Safety Data Sheet | COA/Test Release | User Guide | Product Handling Guide | ||
| Lyo-Ready Direct DNA LAMP Stool, 4x | Stool, LAMP Mixes | LAMP | MDX144 | Order a Sample | Available in 5 mL (1,000 Rxns) or 50 mL (10,000 Rxns) aliquots | Inhibitor tolerance to 20% stool, 2 mg/mL bile salt and 40% Cary Blair media. Perfect for multiplexing and fast cycling conditions. Used in the detection of IBD, cancer, fecal microbiota and bacterial and viruses. |
Yes | No | Lyo-Ready | YesYes | Yes | 4x | Yes | View Details | Safety Data Sheet | COA/Test Release | User Guide | Product Handling Guide | ||
| Lyo-Ready Direct RNA/DNA qPCR Stool, 4x | Stool, Lyo-Ready Mix | RT-qPCR | MDX143 | Order a Sample | Available in 5 mL (1,000 Rxns) or 50 mL (10,000 Rxns) aliquots | Inhibitor tolerance to 5% stool, 2 mg/mL bile salt and 40% Cary Blair media. Perfect for multiplexing and fast cycling conditions. Used in the detection of IBD, cancer, fecal microbiota and bacterial and viruses. |
Yes | No | Lyo-Ready | YesYes | Yes | 4x | Yes | View Details | Safety Data Sheet | COA/Test Release | User Guide | Product Handling Guide | ||
| Lyo-Ready Direct DNA qPCR Stool, 4x | Stool, Lyo-Ready Mix | qPCR | MDX142 | Order a Sample | Available in 5 mL (1,000 Rxns) or 50 mL (10,000 Rxns) aliquots | Inhibitor tolerance to 20% stool, 2 mg/mL bile salt and 40% Cary Blair media. Perfect for multiplexing and fast cycling conditions. Used in the detection of IBD, cancer, fecal microbiota and bacterial and viruses. |
Yes | No | Lyo-Ready | YesYes | Yes | 4x | Yes | View Details | Safety Data Sheet | COA/Test Release | User Guide | Product Handling Guide | ||
| Air-Dryable Direct RNA/DNA qPCR Stool, 4x | Stool, Air-Dryable Mix | RT-qPCR | MDX141 | Order a Sample | Available in 5 mL (1,000 Rxns) or 50 mL (10,000 Rxns) aliquots | Inhibitor tolerance to 5% stool, 2 mg/mL bile salt and 40% Cary Blair media. Perfect for multiplexing and fast cycling conditions. Used in the detection of IBD, cancer, fecal microbiota and bacterial and viruses. |
Yes | Yes | Air-Dryable | YesYes | No | 4x | Yes | View Details | Safety Data Sheet | COA/Test Release | User Guide | Product Handling Guide | ||
| Lyo-Ready Direct RNA/DNA LAMP Saliva, 4x | Saliva, Sputum, LAMP Mixes | RT-LAMP | MDX135 | Order a Sample | Available in 5 mL (1,000 Rxns) or 50 mL (10,000 Rxns) aliquots | Inhibitor tolerance to 60% crude saliva, sputum or mucin samples and 50% UTM. Perfect for multiplexing and fast cycling conditions. Used in the detection of a broad range of diseases, including cancer, respiratory viruses and bacterial infections. |
Yes | No | Lyo-Ready | YesYes | Yes | 4x | Yes | View Details | Safety Data Sheet | COA/Test Release | User Guide | Product Handling Guide | ||
| Lyo-Ready Direct DNA LAMP Saliva, 4x | Saliva, Sputum, LAMP Mixes | LAMP | MDX134 | Order a Sample | Available in 5 mL (1,000 Rxns) or 50 mL (10,000 Rxns) aliquots | Inhibitor tolerance to 60% crude saliva, sputum or mucin samples and 50% UTM. Perfect for multiplexing and fast cycling conditions. Used in the detection of a broad range of diseases, including cancer, respiratory viruses and bacterial infections. |
Yes | No | Lyo-Ready | YesYes | Yes | 4x | Yes | View Details | Safety Data Sheet | COA/Test Release | User Guide | Product Handling Guide | ||
| Lyo-Ready Direct RNA/DNA qPCR Saliva, 4x | Saliva, Sputum, Lyo-Ready Mix | RT-qPCR | MDX133 | Order a Sample | Available in 5 mL (1,000 Rxns) or 50 mL (10,000 Rxns) aliquots | Inhibitor tolerance to 60% crude saliva, sputum or mucin samples and 50% UTM. Perfect for multiplexing and fast cycling conditions. Used in the detection of a broad range of diseases, including cancer, respiratory viruses and bacterial infections. |
Yes | No | Lyo-Ready | YesYes | Yes | 4x | Yes | View Details | Safety Data Sheet | COA/Test Release | User Guide | Product Handling Guide | ||
| Lyo-Ready Direct DNA qPCR Saliva, 4x | Saliva, Sputum, Lyo-Ready Mix | qPCR | MDX132 | Order a Sample | Available in 5 mL (1,000 Rxns) or 50 mL (10,000 Rxns) aliquots | Inhibitor tolerance to 60% crude saliva, sputum or mucin samples and 50% UTM. Perfect for multiplexing and fast cycling conditions. Used in the detection of a broad range of diseases, including cancer, respiratory viruses and bacterial infections. |
Yes | No | Lyo-Ready | YesYes | Yes | 4x | Yes | View Details | Safety Data Sheet | COA/Test Release | User Guide | Product Handling Guide | ||
| Air-Dryable Direct RNA/DNA qPCR Saliva, 4x | Saliva, Sputum, Air-Dryable Mix | RT-qPCR | MDX131 | Order a Sample | Available in 5 mL (1,000 Rxns) or 50 mL (10,000 Rxns) aliquots | Inhibitor tolerance to 60% crude saliva, sputum or mucin samples and 50% UTM. Perfect for multiplexing and fast cycling conditions. Used in the detection of a broad range of diseases, including cancer, respiratory viruses and bacterial infections. |
Yes | Yes | Air-Dryable | YesYes | No | 4x | Yes | View Details | Safety Data Sheet | COA/Test Release | User Guide | Product Handling Guide | ||
| Air-Dryable Direct DNA qPCR Saliva, 4x | Saliva, Sputum, Air-Dryable Mix | qPCR | MDX130 | Order a Sample | Available in 5 mL (1,000 Rxns) or 50 mL (10,000 Rxns) aliquots | Inhibitor tolerance to 60% crude saliva, sputum or mucin samples and 50% UTM. Perfect for multiplexing and fast cycling conditions. Used in the detection of a broad range of diseases, including cancer, respiratory viruses and bacterial infections. |
Yes | Yes | Air-Dryable | YesYes | No | 4x | Yes | View Details | Safety Data Sheet | COA/Test Release | Product Handling Guide | |||
| Lyo-Ready Genotyping Direct qPCR Blood, 4x | Blood, Plasma, Serum, Lyo-Ready Mix | SNP Genotyping | MDX128 | Order a Sample | Available in 1,000 Unit or 10,000 Unit aliquots | Inhibitor tolerance to 10% whole blood, 20% plasma. Compatible with all dual-label probe chemistries for detection of genetic variants, such as single nucleotide and copy number variants, to give highly reproducible allelic discrimination. |
Yes | No | Lyo-Ready | YesYes | Yes | 4x | Yes | View Details | Safety Data Sheet | COA/Test Release | Product Handling Guide | |||
| Lyo-Ready Direct RNA/DNA LAMP Blood, 4x | Blood, Plasma, Serum, LAMP Mixes | RT-LAMP | MDX125 | Order a Sample | Available in 5 mL (1,000 Rxns) or 50 mL (10,000 Rxns) aliquots | Inhibitor tolerance to 10% whole blood, 10% plasma, compatible with all anticoagulants. Perfect for multiplexing and fast cycling conditions. Used in the detection of blood pathogens and liquid biopsy applications. |
Yes | No | Lyo-Ready | YesYes | Yes | 4x | Yes | View Details | COA/Test Release | User Guide | Product Handling Guide | |||
| Lyo-Ready Direct DNA LAMP Blood, 4x | Blood, Plasma, Serum, LAMP Mixes | LAMP | MDX124 | Order a Sample | Available in 5 mL (1,000 Rxns) or 50 mL (10,000 Rxns) aliquots | Inhibitor tolerance to 20% whole blood, 20% plasma, compatible with all anticoagulants. Perfect for multiplexing and fast cycling conditions. Used in the detection of blood pathogens and liquid biopsy applications. |
Yes | No | Lyo-Ready | YesYes | Yes | 4x | Yes | View Details | Safety Data Sheet | COA/Test Release | User Guide | Product Handling Guide | ||
| Air-Dryable Direct DNA qPCR Blood, 4x | Blood, Plasma, Serum, Air-Dryable Mix | qPCR | MDX092 | Order a Sample | Available in 5 mL (1,000 Rxns) or 50 mL (10,000 Rxns) aliquots | Inhibitor tolerance to 20% whole blood, 20% plasma, compatible with all anticoagulants. Perfect for multiplexing and fast cycling conditions. Used in the detection of blood pathogens and liquid biopsy applications. |
Yes | Yes | Air-Dryable | YesYes | No | 4x | Yes | View Details | Safety Data Sheet | COA/Test Release | User Guide | Product Handling Guide | ||
| Lyo-Ready Direct RNA/DNA qPCR Blood, 4x | Blood, Plasma, Serum, Lyo-Ready Mix | RT-qPCR | MDX123 | Order a Sample | Available in 5 mL (1,000 Rxns) or 50 mL (10,000 Rxns) aliquots | Inhibitor tolerance to 10% whole blood, 10% plasma, compatible with all anticoagulants. Perfect for multiplexing and fast cycling conditions. Used in the detection of blood pathogens and liquid biopsy applications. |
Yes | No | Lyo-Ready | YesYes | Yes | 4x | Yes | View Details | Safety Data Sheet | COA/Test Release | User Guide | Product Handling Guide | ||
| Lyo-Ready Direct DNA qPCR Blood, 4x | Blood, Plasma, Serum, Lyo-Ready Mix | qPCR | MDX122 | Order a Sample | Available in 5 mL (1,000 Rxns) or 50 mL (10,000 Rxns) aliquots | Inhibitor tolerance to 20% whole blood, 20% plasma, compatible with all anticoagulants. Perfect for multiplexing and fast cycling conditions. Used in the detection of blood pathogens and liquid biopsy applications. |
Yes | No | Lyo-Ready | YesYes | Yes | 4x | Yes | View Details | Safety Data Sheet | COA/Test Release | User Guide | Product Handling Guide | ||
| Air-Dryable Direct RNA/DNA qPCR Blood, 4x | Blood, Plasma, Serum, Air-Dryable Mix | RT-qPCR | MDX121 | Order a Sample | Available in 5 mL (1,000 Rxns) or 50 mL (10,000 Rxns) aliquots | Inhibitor tolerance to 10% whole blood, 10% plasma, compatible with all anticoagulants. Perfect for multiplexing and fast cycling conditions. Used in the detection of blood pathogens and liquid biopsy applications. |
Yes | Yes | Air-Dryable | YesYes | No | 4x | Yes | View Details | Safety Data Sheet | COA/Test Release | User Guide | Product Handling Guide | ||
| Air-Dryable Direct DNA qPCR Plant, 4x | Plant, Air-Dryable Mix | qPCR | MDX116 | Order a Sample | Available in 5 mL (1,000 Rxns) or 50 mL (10,000 Rxns) aliquots | No need for extraction, compatible with 25% Plant lysate (SDS, NaOH). Perfect for multiplexing and fast cycling conditions for in-field qPCR testing. Used for genotyping and transgene or pathogenic detection. |
Yes | Yes | Air-Dryable | YesYes | No | 4x | Yes | View Details | Safety Data Sheet | COA/Test Release | User Guide | Product Handling Guide |
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Catalogs & Brochures
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